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| 06/02/2010 - StemSave, Inc. teams up with pediatric dentists at Jamaica Hospital to offer New York families access to valuable stem cells.
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StemSave, Inc teams up with pediatric dentists at Jamaica Hospital to offer New York families access to valuable stem cells.
NEW YORK, NY, June 1, 2010 – StemSave™ Inc., the market leader in the field of stem cell recovery and cryo-preservation, announces they are now working with pediatric dentists at Jamaica Hospital to use a new and innovative medical approach to stem cell banking to make it easier for local families to bank their children's stem cells. The partnership marks the first time dentists at Jamaica Hospital will help store their patients’ own stem cells collected from baby teeth, as well as permanent and wisdom teeth, for potential use in medical treatments.
Stem cells are the basis of the emerging field of regenerative medicine. According to research released by the National Institutes of Health (NIH), “Regenerative Medicine is the process of creating living, functional tissues to repair or replace organ function lost due to age, disease, damage or congenital defects. This field holds the promise of regenerating damaged tissues and organs in the body by stimulating previously irreparable organs to heal themselves. Regenerative medicine also empowers scientists to grow tissues and organs in the laboratory and safely implant them when the body cannot heal itself.”
"What makes this breakthrough significant is it gives parents an affordable and convenient opportunity to save their children's stem cells," said Dr. Silvestro Iommazzo, Associate Director Pediatric Dentistry at Jamaica Hospital. “With advancements in stem cell technologies and the discovery of dental stem cells, parents have the opportunity during their children’s natural tooth development - baby teeth and wisdom teeth are ideal stem cell candidates - to recover and bank their own stem cells for potential use in future regenerative medical treatments.”
“We’re proud to extend our network to Jamaica Hospital, and give patients the chance to participate in the most exciting and cutting edge stem cell breakthroughs today,” said Art Greco, CEO of StemSave. “We’re seeing remarkable applications in labs across the country, and we believe now is the time to save your own stem cells so families have the opportunity to take part in the treatments of the future.”
Dr. Iommazzo, along with other pediatric dentists at Jamaica Hospital, work closely with StemSave and parents to ensure that the process is safe, easy, and efficient. Dr. Iommazzo points out that collecting stem cells from teeth is non-invasive because it is done as part of routine dental procedures and at a point when the tooth is already going to come out.
Interested parents should meet with a dentist to find out if their child is a candidate for stem-cell preservation. An eligible tooth has an intact blood supply and should be healthy and free from infection. The ideal baby tooth is a newly loose canine or incisor. An excessively loose tooth or one that has already fallen out is not a viable option because the blood supply to the dental pulp is cut off. While it is better to collect stem cells from younger patients, adults, up to approximately 55 years old, are also eligible to have stem cells collected from their teeth.
StemSave’s network of dentists is the largest in the US and continues to expand rapidly. Through StemSave, dentists are now able to play a greater role in the overall health of their patients by participating in groundbreaking stem cell recovery.
The science and application of stem cells to treat today’s most difficult diseases and injuries is no longer science fiction. With the recent news that stem cells have been used in organ transplants and tooth regeneration, coupled with the US Army’s $250 million investment in regenerative therapies, the promise of stem cells is being recognized today.
If you are interested in banking your child's stem cells from their teeth, please visit www.StemSave.com or call Jamaica Hospital's Dental Clinic at 718-206-6980.
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| 05/25/2010 - Journal of Dental Research: Body's Own Stem Cells Lead to Tooth Regeneration
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| From Dentistry IQ:
Stem cells of body lead to tooth regeneration
NEW YORK--People who have lost some or all of their adult teeth typically look to dentures, or more recently, dental implants to bridge the gap between a toothless appearance.
But this appearance can have a host of unsettling psycho-social ramifications and a tooth-filled grin that is not without pain and discomfort.
Despite being the preferred treatment for missing teeth today, dental implants can fail and have no ability to “remodel” with surrounding jaw bone, which undergoes necessary and unavoidable changes throughout a person’s life.
But a new technique pioneered in the Tissue Engineering and Regenerative Medicine Laboratory of Dr. Jeremy Mao, Edward V. Zegarelli Professor of Dental Medicine, and a professor of biomedical engineering at Columbia University, can orchestrate the body’s stem cells to migrate to three-dimensional scaffold that is infused with growth factor. This can yield an anatomically correct tooth in as soon as nine weeks once implanted in the mouth.
“These findings represent the first report of regeneration of anatomically shaped tooth-like structures in vivo, and by cell homing without cell delivery,” Dr. Mao and his colleagues said in the paper.
“The potency of cell homing is substantiated not only by cell recruitment into scaffold microchannels, but also by regeneration of a putative periodontal ligaments newly formed alveolar bone.”
Dental implants usually consist of a cone-shaped titanium screw with a roughened or smooth surface and are placed in the jaw bone. While implant surgery may be performed as an outpatient procedure, healing times vary widely and successful implantation is a result of multiple visits to certified clinicians, including general dentists, oral surgeons, prosthodontists and periodontists.
Implant patients must allow two to six months for healing and if the implant is installed too soon, it is possible that the implant may move which results in failure. The subsequent time to heal, graft and eventually place a new implant may take up to 18 months.
The work of Dr. Mao and his laboratory, however, holds manifold promise: a more natural process, faster recovery times, and a harnessing of the body’s potential to regrow tissue that will not give out and could ultimately last the patient’s lifetime.
By homing stem cells to a scaffold made of natural materials and integrated in surrounding tissue, there is no need to use harvested stem cell lines, or create a an environment outside of the body (e.g., a Petri dish) where the tooth is grown and then implanted once it has matured.
The tooth instead can be grown “orthotopically,” or in the socket where the tooth will integrate with surrounding tissue in ways that are impossible with hard metals or other materials.
“A key consideration in tooth regeneration is finding a cost-effective approach that can translate into therapies for patients who cannot afford or who aren’t good candidates for dental implants,” Dr. Mao said. “Cell-homing-based tooth regeneration may provide a tangible pathway toward clinical translation.”
This study is published in the Journal of Dental Research, a top journal in the field of dentistry.
This research was supported by NIH ARRA Funding via 5RC2 DE020767 from the National Institute of Dental and Craniofacial Research.
For more information, visit dental.columbia.edu/.
To read more about dental implants, go to www.dentistryiq.com/index/display/article-display/8259726870/articles/dentisryiq/industry/2010/05/biolux-osseopulse.html.
To comment on this topic, go to community.pennwelldentalgroup.com/.
Source: DentistryIQ |
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| 03/10/2010 - From Dentistry IQ: Plasticity in stem cells -- a valuable property for the future of medicine
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You can’t open a newspaper or watch TV without hearing about the incredible advancements in stem cell research, therapies, and applications. Today, this is made possible because of one of stem cells’ most valuable traits, their “plasticity,” — their ability to turn into specific tissues in addition to those from which they are derived. It’s this unique property that is helping transform medicine and dentistry, and shaping the future of regenerative medicine.
Aging is a degenerative process, and as we get older we lose the ability to naturally repair injured or damaged tissues. Stem cells are master cells found throughout our bodies and are responsible for repairing these tissues. Today, dentists in many countries are recovering these valuable stem cells from teeth.
Around the world, researchers are recognizing the plasticity of stem cells and devising ways to control and direct them into many different types of cells and tissues. These cells are then being used to repair damaged and injured tissues and organs. This is the emerging field of regenerative medicine, and it will revolutionize the practice of medicine and dentistry. Utilizing the body’s own repair and maintenance mechanisms, regenerative medicine holds the realistic promise of creating a new paradigm — away from the current “mitigation” approach to treating disease and trauma — to one focused on curing disease and rebuilding damaged tissues and organs.
There are many opportunities to recover stem cells from teeth, but the earlier they are recovered, the more potential they will have for future regenerative therapies. The stem cells recovered from teeth have proved to be very plastic, and they are being introduced into clinical trials.
In Italy researchers recovered stem cells from erupted third molars, expanded these cells in the laboratory, and then reintroduced these stem cells into the same individual from whom they were recovered to repair bone defects in the mandible. In Australia researchers are currently utilizing dental stem cells as a means to treat brain injuries and Alzheimer’s disease. They are observing positive therapeutic results in mice and hope to begin clinical trials using dental stem cells in humans within the next five years. In Japan researchers have differentiated dental stem cells into hepatocytes that might one day be used to treat liver disease. Out of Brazil come published reports that researchers have used dental stem cells to treat dogs with muscular dystrophy. And in Spain researchers are using dental stem cells to treat cardiac disease in animals.
One day, these successful therapies will be applied to humans.
Regenerative medicine
Regenerative medicine is based on three things: stem cells or the raw materials; the extrinsic or intrinsic factors, which tell the stem cells what type of tissue to become; and natural or manufactured scaffolds, which define the shape of growing tissue.
There are several approaches to regenerative medicine. One is in vivo, to introduce extrinsic factors and scaffolds that will home the body’s own natural stem cells to the site of injury. In the body, or in vivo, plasticity is not thought to occur on its own. The stem cells are recruited locally and generally from the type of tissue that they are found in. In degenerative diseases, the local stem cells do not have the capacity to produce enough progenitor cells to repair the damaged tissue.
One of many future solutions is to introduce tissue-specific stem cells to repair these compromised tissues and organs. This will require an accessible source of stem cells that can be programmed into the specific tissue type needed to be repaired. The best cells to use would be an individual’s own stem cells, cells that would be recognized as self and would not be rejected or require the individual to take immunosuppressive medications.
Accessibility
Dental stem cells are proving to be an accessible source of stem cells that have the plasticity to turn into varied types of tissues. Researchers have differentiated dental stem cells in their laboratories into progenitor cells that can produce bone, cartilage, adipose, nervous tissue, muscle, hair, and insulin just to name a few. They have designed tissue-specific “cocktails” which are introduced into the culture medium, directing the stem cells into the desired tissue type.
The dental stem cells are recovered from recently extracted healthy teeth, notably deciduous teeth, developing third molars, and other permanent teeth. Every child will have 20 primary teeth replaced by permanent teeth. In the United States alone, more than 10 million wisdom teeth are being removed and discarded as medical waste on a yearly basis. There are numerous research articles published from around the world that characterize the stem cells recovered from the different types of teeth.
Stem cells recovered from deciduous teeth are immature stem cells that have different characteristics from stem cells recovered from permanent teeth. Deciduous teeth are ectomesenchymal in origin that begin formation at six weeks in utero. They have been shown to contain markers for factors that are found in embryonic stem cells. These factors are responsible for maintaining the “stemness” of these cells, or the ability to replicate indefinitely in vitro or outside of the body.
Unique properties
The proprieties of stem cells recovered from the pulp of deciduous teeth are different from those found in permanent teeth and have been labeled SHED cells for Stem cells from Human Exfoliated Deciduous teeth. SHED cells have also been shown to be more proliferative than bone marrow stem cells. When grown in culture, the SHED cells expand faster and for a longer period of time, generating a larger quantity of cells when compared to bone marrow stem cells.
Stem cells from developing third molars and other developing permanent teeth, e.g. bicuspids removed for orthodontic indications, are also very proliferative. The stage of development of these teeth will determine the potential for these stem cells. A wisdom tooth starts its development around the age of 4 years and begins calcification at the age of 7. The wisdom tooth is considered an organ; it includes nerves, blood vessels, ligaments, bone, enamel, dentin, and cementum. The development of the wisdom tooth starts at the bud stage where it is a collection of undifferentiated mesenchymal stem cells.
Timing
There are different schools of thought on when best to remove wisdom teeth. Removing a wisdom tooth at an earlier stage of development through a germectomy or tooth bud abortion will provide access to a tremendous quantity of pluripotential stem cells that display embryonic stem cell markers. As the wisdom tooth develops and calcifies, there become distinct areas of stem cells that differentiate to produce specific types of tissue.
Once the roots of the third molar begin to develop, there are three main areas of stem cells: the dental pulp, the periodontal ligament, and the apical follicle. When the permanent tooth is fully formed and has erupted, the stem cells are generally confined to the dental pulp. However, in situations where a tooth remains unerupted or impacted, the stem cell-containing follicle may still exist and can be recovered at the time of tooth removal.
As an individual matures, the pulp chambers in teeth also decrease in size. The blood supply within the pulp is reduced as well as the quantity of accessible mesenchymal stem cells. The order of teeth which have dental stem cells with the most potential are deciduous teeth, unerupted deciduous supernumerary teeth (mesodens), developing wisdom teeth, permanent teeth with continued root development (bicuspids or other healthy developing teeth that need to be removed for orthodontic indications), and fully developed and impacted wisdom teeth along with the follicle in adolescents and young adults. Also included are the dental pulp stem cells from healthy permanent teeth in adults.
Regenerative therapies are here today, and the plasticity of stem cells will mold the future of medicine and dentistry. Dental professionals are at the forefront of this emerging field. We have the opportunity to raise awareness of the benefits of stem cell research and provide our patients with the necessary information to make an informed decision on the value of preserving stem cells from healthy teeth when undergoing a planned dental procedure.
Read the entire article at Pennwell's Dentistry IQ:
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| 01/16/2010 - Dental stem cell grows human bone
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Latest research puts dentists at the forefront of life-saving stem cell therapy.
When clinical research moves from animal to successful human trials,
there is a level of certainty that the treatment modality being studied
has reached a level of maturity that puts it well on the road to being
safe and beneficial for the end recipient—the human patient. There is
also the assumption that the trial involves the medical, not the dental
community.
“This breakthrough clinical study uses the patients’ own stem cells
harvested from their own teeth to repair bone. It is the first of what
we believe will be an expanding number of applications to treat a broad
array of diseases, traumas, and injuries,” said Art Greco, CEO of StemSave, a cryogenic dental stem cell bank headquartered in New York City.
“What we are seeing now is a rapid advancement in the use of stem
cells in therapeutic and clinical applications all over the world.
Every major nation around the globe is spending billions of dollars in
developing stem cell-based therapies,” said Greco. One of the reasons
Greco believes there is such urgency in the research is the aging world
population. Without new healthcare treatment modalities, these nations
will go bankrupt trying to treat the elderly conventionally. New
therapies are needed to prolong life and keep people healthy, not just
mitigate their illnesses. “But the best stem cells for use in
stem cell therapy are your own,” said Gregory Chotkowski, StemSave’s
President. “By doing so, the risks of non-biocompatibility and tissue
rejection are negated.” StemSave and other companies like it
are putting dentistry in the forefront of helping to save and preserve
life. Those at StemSave believe stem cell banking will become the
standard of care in the next two to five years. Read the entire article
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| 12/08/2009 - First ever clinical study shows dental stem cells regrow bone
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Leading stem cell company StemSave Inc applauds Italian scientists for breakthrough research that will forever change oral surgery.
NEW YORK – In a statement today, StemSave(TM), Inc., the market leader in the field of stem cell recovery and cryo-preservation lauds research published in the November issue of the European Cells and Materials Journal citing the reconstruction of the human mandible bone with autologous dental pulp stem cells. StemSave commends Italian researchers from the 2nd University of Naples for their groundbreaking work.
This marks the first time dental stem cell research has moved from the laboratory to human clinical trials. The repair and regeneration of bone is particularly significant for the oral maxillofacial field because the repair of these bones, which aid in orofacial functions like speech, chewing, swallowing and facial expressions are extremely intricate and complex.
According to Dr. David Matzilevich, M.D., Ph.D., Science Advisor to StemSave, “these clinical studies are so significant because autologous dental stem cells were expanded in vitro and for the purpose of oro-maxillofacial bone repair. These cells also facilitated the graft, eliminating immunologic complications such as rejection or excessive inflammation. This is compelling because it creates an environment which proves to be more favorable and successful for new mandibular bone to grow. This approach also appears superior to current methodologies utilizing cadaverous tissue or grafting tissue from another part of the body. I am very excited that dental stem cells have emerged as critical players in tissue engineering and regenerative medicine now that they have been proven to differentiate into multiple lineages.”
“This breakthrough clinical study, which uses the patient’s own stem cells harvested from their teeth to repair bone, is the first of what we believe will be an expanding number of applications to treat a broad array of disease, trauma and injury. And because dental stem cells are easy to recover as part of routine dental procedures, this represents the first of many upcoming uses in the field of personal and regenerative medicine and supports the wisdom of banking your own stem cells from your teeth.” said Art Greco, CEO of StemSave, Inc. |
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| 11/13/2009 - Dr. Gregory Chotkowski, President of StemSave, Presenting at the Greater New York Dental Meeting, Wed. Dec 2nd
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The repair of damaged and diseased tissues and the creation of new organs is no longer the future it is happening today. Stem cells and regenerative therapies are an emerging field and the basis for “personalized medicine”. The recent discovery of the valuable source of stem cells found in the pulp of healthy teeth presents new vistas to both medicine and dentistry. These new opportunities will be explored during this presentation.
Title of the Presentation, Stem cells: Sources, Therapies, and The Dental Professional
What you will learn:
• The essentials of stem cell science
• The Current status of a non-invasive methodology for the recovery and cryopreservation of valuable and powerful adult stem cells residing within the pulp of healthy teeth and other oral tissues
• Modern applications of stem cell use in medicine and dentistry
• The role that the orthodontist and pediatric dentist will play in this exciting and emerging field.
Greater New York Dental Meeting, Wednesday Dec 2nd 4pm - 5pm
Program Details
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| 10/27/2009 - StemSave featured in ADHA's ACCESS: Dental Stem Cells in Research and Practice
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StemSave is featured in the cover story of this month's Access Magazine, the Official Publication of the American Dental Hygienists' Association. Jean Majeski's comprehensive overview of the Stem Cell landscape in the Dental industry, the Hygienist's role in the process, and also features Gregory Chotkowski, DMD, President and co-founder of StemSave. Download the complete article here: |
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| 09/29/2009 - StemSave at the upcoming 2009 AAOMS American Association of Oral and Maxillofacial Surgeons Annual Meeting
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StemSave will be exhibiting at The American Association of Oral and Maxillofacial Surgeons (AAOMS) 91st Annual Meeting October 12th – 17th, 2009 in Toronto, Canada. We invite you to stop by Booth #2235 and allow us the opportunity to introduce you to the StemSave™ dental stem cell recovery and cryopreservation service. Built for Dental Professionals, by Dental Professionals, The StemSave Advantage can enhance your practice and expand the level of care that you already offer to your practice’s highly-valued patients.
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| 08/12/2009 - StemSave is featured on WPVI ABC 6 News in Philadelphia.
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If parents missed the chance to bank their children’s umbilical cord
blood, they now have the opportunity to bank their children’s stem cells found in teeth. WPVI ABC News reports Carolina Coll, a mother in Philadelphia, PA
missed the opportunity to bank her older child’s umbilical cord blood
but was able to bank his teeth stem cells thanks to her dentist, Dr. Gomez utilizing StemSave’s stem cell banking service. Margaret Keller, Associate Professor at Coriell Institute and director of Coriell
Stem Cell Biobank, states that these stem cells have the potential to
be differentiated into bone, heart, muscle and other tissue for use in
future regenerative medical therapies.
Click Here to view the video
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| 05/30/2009 - Google Director Christopher Theodoros Joins StemSave Senior Management Team
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StemSave(TM), Inc, a market leader in the field of stem cell
recovery and cryo-preservation, announces today that S Christopher
Theodoros has joined its senior management team. Theodoros, recently
Director of Industry Relations for Google, Inc., will be responsible
for leading StemSave’s growth and leadership in the biotech field as
well as spearheading innovative digital marketing efforts.
“Chris joins at a crucial time for StemSave as we’re seeing renewed
interest and investment from the Obama administration and heightened
interest and investment from the private sector in the field of stem
cell research,” said Art Greco, CEO of StemSave. “Stem cell research,
technology and medicine are advancing at an exponential pace and
StemSave gives people the ability to tap into those innovations by
providing an affordable and non-invasive method for the recovery and
cryo-preservation of the powerful adult stem cells found in teeth by
teaming up with dentists to recover stem cells during routine dental
procedures.
Chris brings a level of expertise and insight from growing early
stage companies that will help lead StemSave’s ramp up during these
exciting times where StemSave makes it possible for anyone with access
to a dentist to have the ability to procure their own stem cells for
use in future regenerative medical therapies.” Read entire article
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| 03/24/2009 - Stem Cells in Teeth Open New Possibilities for Dental Practices - Article featured in WDJ written by Gregory Chotkowski, DMD, OMS, President, StemSave Inc.
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In research centers, universities, and hospitals around the world,
there are remarkable scientific advancements giving families the
ability to recover valuable stem cells for use in future regenerative
medical applications With the recent discovery of powerful stem cells
within deciduous teeth and third molars, both children and adults now
have the opportunity to recover and cryo-preserve their stem cells both
noninvasively and affordably, giving dentists the opportunity to be on
the frontlines of medicine’s most exciting developing field.
Dentists can now play a larger role in their patient’s overall
health by assisting them in the recovery and cryo-preservation of the
patient’s own very powerful stem cells. Introducing StemSave into a
dental practice gives dental practitioners an opportunity to delve
deeper into their patients’ health concerns and to offer a valuable
service that transcends oral health. Indeed, it speaks to the future
health of the entire being.
Stem cells are unique in that they are the only cells in our body
that can regenerate. They are the repair and maintenance cells of the
body and are the key to unlocking the promise of regenerative medicine.
The foundation of this type of medicine is based on the body’s own
natural reparative abilities; the stem cells’ abilities to replace
damaged tissue caused by aging, disease, and injury. Another unique
feature of certain types of stem cells is their ability to
differentiate, meaning that in addition to their ability to regenerate,
they can turn into a broad range of specialized cells. This enables
stem cells to regenerate organs, tissues, bones, and much more. We are
witnessing stem cell therapies being developed to treat disease and
trauma such as Parkinson’s, Alzheimer’s, diabetes, MS, arthritis, heart
disease, spinal cord injuries, joint replacement, genetic diseases, and
many more. Read entire article in the WDJ
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| 03/18/2009 - StemSave Exhibiting at the 97th Thomas P. Hinman Dental Meeting March 19-21, 2009 - Atlanta, Georgia
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was great meeting you at the Hinman Dental Meeting in Atlanta. For those of you that
visited our booth, and would still like to recieve the complimentary
Code for the 4-Credit CE Course entitled: Stem
Cells: Sources, Therapies and the Dental Professional, please contact us at info@StemSave.com or call us at 877.StemSave.com. We look forward to seeing you again next year. |
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| 03/04/2009 - New York State Dental Foundation launches online CE course on stem cells and the dental professional
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The repair of damaged and diseased tissues and the creation of new organs is no longer the future, it is happening today. Daily, we hear the media reporting on stem cell breakthroughs and how they are being applied clinically to save lives. Stem cells and regenerative therapies are an emerging field and the basis for "personalized medicine". Dental Professionals have the opportunity to participate at the genesis of this new and exciting area of biotechnology.
Dr. Gregory Chotkowski, DMD will present on the recently discovered and valuable source of stem cells found in the pulp of healthy teeth. His discussion will include basic stem cell science, the current research and the future they hold for both Dentistry and Medicine
Read and learn more
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| 03/02/2009 - Stem Cells: What will they be when they grow out?
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Scientists are now developing a number of strategies in the
laboratory for producing dopamine-releasing neurons from human adult
stem cells to be transplanted into humans with Parkinson's disease. If
the generation of an unlimited supply of dopamine-producing neurons is
successful, neurotransplantation may be widely available for
Parkinson's patients in the future.
Parkinson's disease is just one of many previously incurable
diseases and conditions that may find a cure in stem cell regenerative
therapies. Muscular dystrophy, Alzheimer's disease, osteoporosis,
diabetes, cardiovascular disease, renal failure, and spinal cord
injuries are a few others. Virtually any disease that occurs as a
result of damaged, failing or malfunctioning tissues may potentially be
cured through regenerative therapies.
Stem cells from one part of the body will be expanded (grown out)
and reimplanted to replace an entirely different type of tissue. This
type of transplant will totally negate the need for antirejection
drugs, since the implant is made of the patient's own body cells.
Jeremy Mao, DDS, PhD, a professor and director of the Tissue
Engineering and Regenerative Medicine Laboratory and professor of
dentistry at Columbia University, states that, although more clinical
research and differentiation studies are needed involving dental stem
cells, the future holds a great potential for the use of these cells.
Clinical research of the potential for utilizing these cells in the
treatment of diseases or conditions involving neural, bone, cartilage,
or fat is just beginning.
Dr. Mao's latest announcement states in an abstract that he has
turned dental stem cells into pancreatic beta islet cells that produce
insulin. Considering the fact that the occurrence of diabetes in the
United States is reaching epidemic proportions, this is most exciting! Read the entire article
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| 02/27/2009 - Your Child's Teeth Can Save their Life using StemSave service - as found in Working Mother Magazine By Lauri Harrison
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Wait! Before you plan for the tooth fairy to come and take away your child’s tooth, consider preserving it for future use Believe it or not, the human tooth contains healthy pulp tissue which contains stem cells that can be utilized to regenerate your child’s health if needed. Sounds like a Sci-Fi movie, but it’s not. It works along the same principles as preserving the cord blood when your baby is born. Stem cells extracted from the healthy tissue within your child’s tooth can help fix medical ailments, grow new organs, repair bone, and much more.
There are more than 70 people currently in clinical trials right now, and the potential is incredible. Science is moving forward very quickly. Stem cells from teeth are a back-up insurance plan for your child. You don’t have to sacrifice a tooth. In fact, you work with your dentist to ensure that a healthy, loose tooth is taken out while there is still active blood supply to the tooth. The dentist can put up to four teeth in a vial that contains nutrients to keep the stem cells alive, and puts the teeth into hypothermia. The vial is shipped overnight to a company called Stem Save for preservation until you need it. The teeth are saved for your child and are not used for research. This whole process is coordinated with your dentist and Stem Save. All you have to do is set up the account, which can be done completely online. Stem Save and your dentist take care of everything for you.
If at some point in the future your child would need an organ transplant, bone marrow, skin, etc., their body will not run the risk of rejecting those from a donor because their own stem cells would be utilized. Currently, the Army is utilizing this method to help wounded soldiers heal from their injuries.
What exactly are stem cells? They are the carriers for repaired DNA and are capable of replicating themselves. Research studies have discovered that stem cells from teeth are some of the most powerful stem cells in the entire human body. Interestingly, these stem cells can replicate at a faster rate and for a longer period of time than stem cells which have been harvested from other tissues within the body. As your body ages, the regenerative capabilities slow down so the earlier in life the stem cells are obtained, the more valuable they will be when they are needed most.
What will storing your family's stem cells from teeth do for you?
Protect your child’s future health.
Practically eliminate the potential risk of cell rejection and other complications.
This is an opportunity that is available now, is safe, convenient and affordable.
Since younger stem cells grow faster and for longer periods of time, they have less potential for mutations. Therefore these stem cells will be more effective when needed for future regenerative therapies. If you are curious and would like to learn more, visit StemSave.com and talk to your family’s dentist about this opportunity. Even if your dentist is not included in the web site directory, you can still have your dentist do this for you. New dentists are added each and every day.
Think about all the teeth that have been collected and saved for baby books or just thrown away that could have been used. Its secondary insurance worth having, wouldn’t you agree?
Read entire article Visit the MomToBeDepotBlog
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| 02/27/2009 - StemSave exhibiting at the 144th Midwinter Dental meeting in Chigago February 27th - March 1st.
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Stop by booth #1060 to learn more about the StemSave Recovery and Cryopreservation service, we will be handing out our CE course booklet Stem Cells: Sources, Therapies and the Dental Professionals. Drop by, say hello and will provide you with a code to receive 4 complimentary CE credits.
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| 02/20/2009 - Saving lives one tooth at a time using the StemSave service
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Researchers from the National Institute of Health discovered the
presence of stem cells in teeth. Dentists familiar with the research
formed a company called StemSave in order to store the stem cells from
extracted teeth for later use if the patient needs to treat a disease
or injury with stem cells - the body’s only natural regenerative cells
which can grow many different types of tissue.
Dr. Robert Carpenter who owns a practice in Saratoga Springs
has joined StemSave to become one of the first dentists in the area to
collect and store personal stem cells for future use. There are two
types of stem cells, Carpenter said. First are the ever-controversial
embryonic stem cells which come from human embryos, and second are
adult stem cells which are already in every adult’s body and can
regenerate into many different types of cells.
“There is a high quantity and quality of stem cells in teeth which
are very ‘plastic,’ meaning they are easily multiplied and are easy to
stimulate new growth in so many types of tissue,” he said. Stem cells
can be harvested in routine procedures that dentists perform every day
in the office. The best stem cells come from adult wisdom teeth or baby
teeth before they become loose. Once the teeth are extracted the cells
are preserved and are stored for whenever the patient may need them.
What is unique about using stem cells from teeth is that the cells come
from the patient’s own body, not someone else’s, like using embryonic
stem cells. There is no chance that the body will reject the cells or
become diseased. “The potential here is unbelievable. We really are at
the tip of the iceberg in realizing what we can do with these stem
cells,” Carpenter said. “And to think that they are readily available
with procedures that are done every day.” Read entire the article |
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| 02/11/2009 - Pulling Stem Cells from wisdom teeth - Oral Surgeon utilizes StemSave
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Many Individuals are willing to pay the money to preserve their
teeth and for the chance of a cure later in life. Dr. John Lupori of
Alpine Oral and Facial Surgery in Steamboat Springs first collected
teeth for a storage bank several weeks ago and has done it a few times
since then.
For Miriam Pensack’s family, it wasn’t a difficult decision.
The 17-year-old from Steamboat Springs has the same heart condition
that caused her father to get a heart transplant. She was unconscious
at Lupori’s office, about to get her wisdom teeth pulled, when her dad
learned about StemSave, a New York company that stores dental stem
cells.
“If, God forbid, I needed a heart transplant, . . . we think stem
cells would be hugely beneficial,” said Pensack, who learned through
genetic testing that she had inherited hypertrophic cardiomyopathy, a
disease of the heart muscle that can cause sudden death in athletes.
The teenager’s father, physician and psychiatrist Robert Pensack,
said he wasn’t thinking just of Miriam’s heart condition when he
decided to save her dental stem cells.
“It’s my personal belief that stem cells are going to revolutionize
medicine,” he said. “As she ages, as all of us will, she could come
down with all kinds of other illnesses.” Read entire article
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| 02/03/2009 - Banking Stem Cells For Future Use - StemSave and Fast Company Magazine
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A personal banking system for stem cells
We’ve all heard about the promise of stem cells: Chinese doctors are
experimenting with treatments for neurological diseases, and Spanish
surgeons made headlines last fall after they grew a new section of
windpipe for a woman using her own cells. While much of the research
and most of the therapies are still figments of scientists’
imaginations, a New York-based company called StemSave is offering to
bank your own cells in anticipation of the day when potential is turned
into reality.
StemSave harvests stem cells from teeth already pulled by your
dentist, which are delivered to its lab in a patented transportation
kit that keeps cells alive by chilling them. All stem cells aren’t
created equal, but StemSave CEO Art Greco claims that cells from teeth
are particularly versatile — and the younger the tooth, the better. The
service costs $590 to join, and $100 per year after that. Read entire article
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| 02/02/2009 - Doctor in Colorado utilizes StemSave to preserve stem cells in wisdom teeth to combat a rare genetic cardiac disorder.
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Miriam Pensack went to Alpine Oral and Facial Surgery to have her
wisdom teeth pulled in November, when she awoke she learned that her
father had chosen to have her stem cells saved.
When Lupori removed Miriam’s teeth, he checked to make sure the pulp
was there and put them into a preserving solution. The office shipped
the teeth to New York. StemSave’s laboratory workers tested them for
viable stem cells and stored Miriam’s tissue.
Pensack, a former emergency room doctor who now is a psychiatrist,
didn’t hesitate when he learned he could have Miriam’s cells saved. He
has hypertrophic cardiomyopathy, a condition in which the muscle of the
heart is abnormal without an apparent cause. It’s genetic.
If stem cell research advances to the state he thinks it will, people could have diseased heart tissue
replaced with healthy tissue grown from their own cells.
One of the benefits of growing a new organ from your own stem cells
is that you don’t have any risk of the body rejecting it, Pensack said.
Pensack underwent a heart transplant because of his condition. He takes
two drugs to keep his immune system from rejecting the organ. He takes
13 drugs to treat the side effects of those two.
“You take them forever, and they’re all like chemotherapy,” Pensack said. “They’re poisonous to other organs.”
Miriam said her family frequently discussed the potential of stem
cells. She’s glad hers are on ice because they could help her deal with
any medical issue she encounters.
“Hopefully, should complications come up in my health, that is a pretty firm pillar to lean on,” Miriam Pensack said. Read Article View Video
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| 01/26/2009 - StemSave will be exhibiting at the Yankee Dental Conference in Boston January 29th - 31st.
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| It
was great meeting you at the Yankee Dental Meeting in Boston. For those of you that
visited our booth, and would still like to receive the complimentary
Code for the 4-Credit CE Course entitled: Stem
Cells: Sources, Therapies and the Dental Professional, please contact us at info@StemSave.com or call us at 877.StemSave.com. We look forward to seeing you again next year in Boston. |
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| 01/18/2009 - Stem Cells: How baby teeth can save your life
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Dr Joanne Oppenheim is a Pediatric Dentist in Chicago and was featured in an article that appeared in Woman Dental Journal, Stem Cells: How Baby Teeth Can Save Your Life.
The value of stem cells in the curing of so many of the deadliest
diseases is much better understood today. If we can save the stem cells
from baby teeth, it is like receiving another opportunity for the
people who did not save their babies' cord blood.
In the spring of 2008, I read an article about preserving the stem
cells from baby teeth. My first thought was that it was a waste having
all of my children’s teeth sent to the tooth fairy instead of to StemSave. During the annual American Academy of Pediatric Dentistry meeting in May, I spoke with the people at the StemSave table. They were doing the same thing with baby teeth as the people 12 years ago were doing with the cord blood. Once parents
choose to save their child’s baby teeth, we explain to the child that
we will give them a special tooth box and the tooth fairy will still
come to their house. There is so much emotion and nostalgia associated
with losing baby teeth. While parents may want to take the traditional
under-the-pillow route with the first tooth, we try to create a new
sense of excitement with sending the tooth off to StemSave.
We encourage the child to draw a picture or write a note to let the
tooth fairy know where the tooth is and that we only need the stuff on
the inside and she can take the stuff on the outside! Sources of Dental Stem Cells In
a child, the most accessible stem cells are from the oral cavity. For
deciduous teeth, the best candidates are moderately resorbed canine and
incisors with the presence of healthy pulp. In children, other sources
of easily accessible stem cells are supernumerary teeth, mesodens,
over-retained deciduous teeth associated with congenitally missing
permanent teeth, and prophylactically removed deciduous molars for
orthodontic indication. Read the entire WDJ article
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| 01/08/2009 - Doctors recommend StemSave for banking stem cells from teeth for those parents who missed the opportunity to save their children’s cord blood
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As seen on the nationally syndicated CBS program ‘The Doctors,’ powerful stem cells found in teeth provide parents with a ‘second opportunity’ to save stem cells.
View ‘The Doctor’s’ Video
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| 12/27/2008 - StemSave president Dr. Greg Chotkowski discusses stem cells, regenerative medicine and the recovery and cryo-preservation of stem cells found in teeth on AM Arizona.
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StemSave, Inc is a collaborative effort between stem cell researchers and the dental community to provide families, individuals and stem cell researchers a cost effective, non-invasive methodology for the recovery and cryopreservation of powerful and valuable Adult Stem Cells residing within baby teeth, wisdom teeth, permanent teeth and other oral tissues for future use in personalized medicine and regenerative medical therapies. For more information, visit www.StemSave.com.
View the AM Arizona Video |
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| 12/09/2008 - Fox News Report Stem Cells in teeth could potentially save lives.
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A Phoenix Oral Surgeon and a StemSave Dental Professional, Dr. Jack Buhrow, provides the StemSave Recovery and Cryopreservation Service for a 21 year old woman at the time her wisdom teeth are being extracted. The Stem Cells contained in the healthy pulp of teeth could be used for future regenerative purposes.
View FOX News video |
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| 12/08/2008 - StemSave and Hu-Friedy announce partnership on stem cell education
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NEW YORK, NY, October 21, 2008 – StemSave(TM), Inc, a market leader in the
field of stem cell recovery and cryo-preservation, announced today its partnership
with Hu-Friedy’s online dental hygiene community, Friends of Hu-Friedy to offer a new continuing education (CE) course on the role dental professionals can play in both the recovery and future use of stem cells.
The CE class was developed in collaboration with StemSave’s president, Dr. Gregory Chotkowski, DMD, OMS and is titled: Stem Cells: Emerging Medical and Dental Therapies and the Dental Professional. StemSave and Hu-Friedy are making the course complimentary to registered members, known as ‘friends of Hu-Friedy’, until the end of October. |
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| 11/22/2008 - DISCOVERY OF STEM CELLS IN TEETH PUTS DENTISTRY AT THE FOREFRONT OF THE EMERGING FIELDS OF REGENERATIVE AND PERSONALIZED MEDICINE
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Columbia University professor Dr
Jeremy Mao to present his research findings on dental stem cells & Discuss
the medical, health care and business implications of preserving patients’
dental stem cells
Presented at the Greater New
York Dental Meeting (GNYDM), Jacob
K Javits
Center in New
York City, Wednesday, December 3rd at11:45am.
More than 55,000 health care professionals will
gather at the Greater NY Dental Meeting where Dr. Jeremy Mao, DDS, PhD will discuss the medical applications
of dental stem cells and how dentists can incorporate this groundbreaking
discovery into their practices.
Dentists are now in the unique position of
being able to help patients preserve their own stem cells. Instead of discarding a patient’s tooth
during a routine medical procedure, a new technology allows dentists to
preserve these teeth so patients can bank their stem cells.
Dr. Mao, one of the leading stem cell
researchers in the world, will discuss his latest scientific findings and why dentists
should expand their practice to incorporate the recovery and cryo-preservation of
dental stem cells on behalf of their patients.
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| 10/21/2008 - THE FRIENDS OF HU-FRIEDY PROGRAM LAUNCHES A NEW CONTINUING EDUCATION COURSE: Stem Cells: Emerging Medical and Dental Therapies and the Dental Professional
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CHICAGO,
IL – Hu-Friedy’s online dental hygiene community, Friends of Hu-Friedy is
designed exclusively for RDHs, dental hygiene students and faculty, the program,
which offers professional support for its members in various ways, now includes
complimentary CE courses. The membership program’s CE catalog currently offers
multiple courses with the newest addition titled: Stem Cells: Emerging Medical and Dental Therapies and the Dental
Professional. As a special introductory offer, Stem Cells: Emerging Medical and Dental Therapies and the Dental
Professional will be complimentary to all members (no Hu-Points needed to
redeem for credit!) now through October 31st , 2008! The
2 CEU course was developed in collaboration with Dr.
Gregory Chotkowski, DMD, president of StemSave, Inc. The course centers on how
the dental professional will play an important role in both the recovery
and the future use of stem cells in Dental and Medical regenerative and
personalized therapies.
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| 10/20/2008 - October 16th - 19th The American Dental Association's Annual Session, San Antonio TX
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It
was great meeting you at the ADA meeting in San Antonio. For those of you that
visited our booth, and would still like to recieve the complimentary
Code for the 4-Credit CE Course entitled: Stem
Cells: Sources, Therapies and the Dental Professional, please contact us at info@StemSave.com or call us at 877.StemSave.com. We look forward to seeing you again next year.
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| 10/19/2008 - Dentaltown - On Line CE - Stem Cells: Emerging Medical and Dental Therapies for the Dental Professional
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Speaker: Jay B Reznick, DMD, MD
Synopsis:
Recent exciting discoveries place dentists at the forefront
of engaging their patients in potentially life-saving therapies derived from a
patient's own stem cells located in deciduous and permanent teeth. Adult stem
cells, including dental stem cells, have the potential, like bone marrow-derived
stem cells and adipose-derived stem cells, to cure a number of diseases.
In medicine, stem cell-based treatments are being used and investigated
for conditions as diverse as Parkinson's disease neural degeneration following
brain injury, cardiovascular disease and autoimmune diseases. Stem cells will be
used in dentistry for the regeneration of dentin and/or dental pulp,
biologically viable scaffolds will be used for the replacement of orofacial bone
and cartilage, and defective salivary glands will he partially or completely
regenerated. Dental stem cells can he obtained from the pulp of the primary and
permanent teeth, from the periodontal ligament, and from associated healthy
tissues. Exfoliating/extracted deciduous teeth and permanent teeth extracted for
orthodontic treatment, trauma or dental implant indications are all readily
available sources of dental stem cells. The harvest of these dental stem cells
results in minimal trauma. Dental professionals have the opportunity to make
their patients aware of these new sources of stem cells that can be stored for
future use as new therapies are developed for a range of diseases and injuries.
Dentaltown
- On Line CE - Stem Cells: |
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| 09/20/2008 - StemSave, Inc. Moves Corporate Headquarters to New York City
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NEW YORK, NY, Sep 16 (MARKET WIRE) --
StemSave(TM), Inc, a market leader in
the field of stem cell recovery and cryo-preservation, announced today that
effective immediately, it is moving its corporate headquarters to New York
City (its lab and cryo-preservation facilities will remain in
Massachusetts). Arthur
E. Greco, CEO, made the announcement today from the company's new
offices in Manhattan. "Not only does this move bring our corporate offices
closer to our scientific advisors, it places us in one of the global
epicenters of stem cell research. In addition, it allows us to participate
in New York State's $600 million stem cell research initiative. This is an
enormous opportunity for us and for the families we serve." StemSave's
scientific advisory council includes Dr. Jeremy Mao, DDS,
PhD, a Director of the Tissue Engineering and Regenerative Medicine
Laboratory (TERML) and a Professor at Columbia University, and Gordana Vunjak-Novakovic,
PhD, a Director of the Laboratory for Stem Cells and Tissue Engineering
and Professor of Biomedical Engineering at Columbia University.
Read
entire article
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| 09/18/2008 - September 16th - 20th The AAOMS 90th Annual Meeting, Seattle Washington
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StemSave
will be exhibiting at The American Association of Oral and Maxillofacial
Surgeons 90th Annual Meeting September 16th – 20th, in Seattle, Washington.
We invite you to stop by Booth #1608 and allow us the opportunity to introduce
you to the StemSave™ dental stem cell recovery and cryopreservation service.
StemSave™ can enhance your practice and expand the level of care that you
already offer to your practice’s highly-valued patients.
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| 09/17/2008 - Adelaide research to repair brain damage with stem cells from teeth
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September 15, 2008 11:30pm
STROKE victims could one day give their back teeth to repair brain injuries, an Adelaide researcher predicts.
A team of scientists is investigating using stem cells harvested from adult teeth to repair brain damage.
It will be led by the newly created Centre for Stem Cell Research, which was launched yesterday at the University of Adelaide.
Almost 100 scientists and 80 students from 18 research groups across
Adelaide are involved with the centre, which plans to develop therapies
for diseases such as stroke, heart attack, cancer and cystic fibrosis.
It has been established that cells from adult teeth can be used to
create stem cells that have the ability to form new brain tissue.
An experiment has begun to see whether these cells can repair stroke damage in the brains of rats.
Dr Simon Koblar of the University of Adelaide said human clinical
trials would follow within five years if the experiments worked.
Dr Koblar said most of his patients in the clinic at Queen Elizabeth
Hospital "would give gladly some of their teeth" to see even a small
improvement in movement and brain function after a stroke.
"At the moment all I can do is, from day to day, say `wait and see'," he said.
Centre director Associate Professor Stan Gronthos was one of the
first to realise that teeth stem cells were "a little bit different".
"They have the ability to form different structures in the craniofacial region including brain tissue as well," he said.
Researcher Dr Agnes Arthur helped prove stem cells from adult teeth
could make brain cells. Her work has been published in the journal Stem Cells.
She said she wanted to do something that could have clinical
implications, "down the track" and was happy with the way the research
turned out.
Read
article
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| 09/02/2008 - September 6-9 The American Academy of Periodontology's 94th Annual Meeting in Seattle Washington.
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It was great meeting you at
the AAP's 94th Annual Meeting September 6-9 at the Washington State
Convention and Trade Center in Seattle.
For those of you that visited our booth,
we will be emailing you the complimentary Code for the 4-Credit CE Course
entitled: Stem Cells:
Sources, Therapies and the Dental Professional. We look
forward to you enrolling as a StemSave Dental Professional.
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| 08/06/2008 - WEBCAST Stem Cells: Sources, Therapies and the Dental Professional, Speaker: Fiona Collins, MBA, MA On-demand 30 minutes in length
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Overview:
Recent exciting discoveries place dentists at the forefront of engaging their patients in potentially life-saving therapies derived from a patient's own stem cells located in deciduous and permanent teeth. In medicine, stem cell-based treatments are being used and investigated for conditions as diverse as Parkinson's disease, neural degeneration following brain injury, cardiovascular disease and autoimmune diseases. Stem cells will be used in dentistry for the regeneration of dentin and/or dental pulp, biologically viable scaffolds will be used for the replacement of orofacial bone and cartilage, and defective salivary glands will be partially or completely regenerated.
Dental stem cells can be obtained from the pulp of the primary and permanent teeth, from the periodontal ligament, and from associated healthy tissues. Exfoliating/extracted deciduous teeth and permanent teeth extracted for orthodontic treatment, trauma or dental implant indications are all readily available sources of dental stem cells. The harvest of these dental stem cells results in minimal trauma. Dental professionals have the opportunity to make their patients aware of these new sources of stem cells that can be stored for future use as new therapies are developed for a range of diseases and injuries.
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| 07/05/2008 - July 16th - 20th AGD Annual Meeting in Orlando Florida
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It
was great meeting you at The Academy of General Dentistry Annual Meeting. For those of you that
visited our booth, we will be emailing you the complimentary Code for
the 4-Credit CE Course entitled: Stem Cells: Sources, Therapies and the Dental Professional. We hope you enjoyed Dr. Vanstrom's presentation
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| 05/05/2008 - May 22nd - 25th: The American Association of Pediatric Dentist, Washington, DC
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| It was great meeting you at the AAPD meeting. For those of you that visited our booth, we will be emailing you the complimentary Code for the 4-Credit CE Course entitled: Stem Cells: Sources, Therapies and the Dental Professional. We look forward to seeing you again next year in Hawaii |
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| 04/28/2008 - May 1st – May 4th: The California Dental Association’s Spring Scientific Meeting, Anaheim, CA
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| It was great meeting you at the CDA Spring Scientific meeting. We look forward to seeing you again at the fall CDA meeting. |
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| 04/19/2008 - April 17th – 19th: DentalTown’s 6th Annual Townie Meeting, Las Vegas, NV
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It was great meeting you at the Townie Meeting. For those of you that visited our booth, and would still like to recieve the complimentary Code for the 4-Credit CE Course entitled: Stem
Cells: Sources, Therapies and the Dental Professional, please contact us at info@StemSave.com or call us at 877.StemSave.com. We look forward to seeing you again next year.
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| 04/14/2008 - 4/14/2008 Published Article: Stem Cells and the Future of Dental Care. Jeremy J. Mao, DDS, Ph.D, New York State Dental Journal, March 2008.
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Abstract:
What
are stem cells? As dentists, why should we be concerned with stem cells? How
would stem cells change dental practice? Is it possible to grow a tooth or TMJ
with stem cells? This article summarizes the latest stem cell research and
development for dental, oral and craniofacial applications. Stem cell
research and development will, over time, transform dental practice in a
magnitude far greater than did amalgam or dental implants. Metallic
alloys, composites and even titanium implants are not permanent solutions. In
contrast, stem cell technology will generate native tissue analogs that are
compatible with the patient’s own.
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| 04/14/2008 - April 3rd - 5th 2008 Western Regional Dental Meeting Phoenix AZ
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Thank you for stopping by our booth and allowing us to introduce you to StemSave. We look forward to seeing you again next year.
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Sign up now to receive up-to-the-minute email news on StemSave and the current breakthroughs
happening in the field of stem cell research and regenerative medicine.
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